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, 15 , 578-584, Rosen, H., and Klebanoff, S

TMA syndromes require rapid intervention with plasmapheresis, immunosuppressive agents (corticosteroids), or complement-inhibiting therapies (e.g., eculizumab) due to their natural pathophysiology of endothelial damage and complement dysregulation

Padilla, K

After removal of cellular proteins in the supernatant, this precipitant is then solubilized in low-salt reducing buffer, reversing the phase transition and inducing C-terminal cleavage of the intein